Interaction of beta Adrenergic Blockade and Certain Vasodilators in Dextran-Induced Rat Paw Edema
| Autor: | Gordon R. McKinney, Paul M. Lish |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
medicine.medical_specialty
Beta-adrenergic blocking agent Epinephrine Adrenergic receptor Chemistry Vasodilator Agents Dextrans Hydralazine General Biochemistry Genetics and Molecular Biology Rats Phentolamine Endocrinology Internal medicine Edema Isoxsuprine Sympatholytics medicine Animals medicine.symptom Antagonism medicine.drug |
| Zdroj: | Experimental Biology and Medicine. 121:494-496 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-121-30813 |
| Popis: | SummaryThe antagonism by a potent beta adrenergic blocking agent, MJ 1999, of the inhibition of dextran-induced rat paw edema by epinephrine was demonstrated. MJ 1999 did not antagonize the inhibition by either isoxsuprine or hydralazine as effectively as that by epinephrine. The importance of the beta receptor stimulating component in epinephrine inhibition was further seen by the lack of antagonism by phentolamine, an alpha blocking agent. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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