Meta‐analysis of the association between chromosomal polymorphisms and outcomes of embryo transfer following in vitro fertilization and/or intracytoplasmic sperm injection
| Autor: | Ling Sun, Zhi-Heng Chen, Zhanhui Ou, Min-Na Yin |
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| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty medicine.medical_treatment Reproductive technology Intracytoplasmic sperm injection 03 medical and health sciences Sex Factors 0302 clinical medicine Human fertilization Pregnancy Outcome Assessment Health Care medicine Humans Sperm Injections Intracytoplasmic Birth Rate reproductive and urinary physiology Gynecology Polymorphism Genetic 030219 obstetrics & reproductive medicine In vitro fertilisation urogenital system business.industry Obstetrics and Gynecology General Medicine Odds ratio Embryo Transfer Embryo transfer 030104 developmental biology Case-Control Studies Meta-analysis embryonic structures Female business Live birth |
| Zdroj: | International Journal of Gynecology & Obstetrics. 144:135-142 |
| ISSN: | 1879-3479 0020-7292 |
| DOI: | 10.1002/ijgo.12702 |
| Popis: | BACKGROUND The outcomes of in vitro fertilization and/or intracytoplasmic sperm injection (IVF/ICSI) are contradictory among individuals with chromosomal polymorphisms. OBJECTIVES To assess whether chromosomal polymorphisms affect the outcomes of assisted reproductive technologies. SEARCH STRATEGY Four online databases were searched from inception to September 18, 2017, using terms including "chromosomal polymorphisms" and "In vitro fertilization." SELECTION CRITERIA The meta-analysis included studies published in any language on IVF/ICSI outcomes in relation to male and/or female chromosomal polymorphisms (n=8). DATA COLLECTION AND ANALYSIS Data were extracted using a predesigned form. The IVF/ICSI outcomes were then pooled and their heterogeneity assessed. MAIN RESULTS Male chromosomal polymorphisms showed lowered values for fertilization rate (odds ratio [OR] 1.29, 95% confidence interval [CI] 1.09-1.54; P=0.004); cleavage rate (OR 2.65, 95% CI 1.88-3.72; P |
| Databáze: | OpenAIRE |
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