APRI and FIB-4 are good predictors of the stage of liver fibrosis in chronic hepatitis B: the Chronic Hepatitis Cohort Study (CHeCS)

Autor:	E, Teshale, M, Lu, L B, Rupp, S D, Holmberg, A C, Moorman, P, Spradling, V, Vijayadeva, J A, Boscarino, M A, Schmidt, S C, Gordon, Lois, Drew
Rok vydání:	2014
Předmět:	Liver Cirrhosis Male medicine.medical_specialty Liver fibrosis Sensitivity and Specificity Severity of Illness Index Gastroenterology Cohort Studies Hepatitis B Chronic Chronic hepatitis Fibrosis Virology Internal medicine medicine Humans Aspartate Aminotransferases Stage (cooking) Hepatology medicine.diagnostic_test Platelet Count AST/ALT ratio business.industry Alanine Transaminase Fibrosis stage Middle Aged medicine.disease Infectious Diseases Liver biopsy Female business Biomarkers Cohort study
Zdroj:	Journal of Viral Hepatitis. 21:917-920
ISSN:	1352-0504
DOI:	10.1111/jvh.12279
Popis:	Summary We aim to determine the predictive ability of APRI, FIB-4 and AST/ALT ratio for staging of liver fibrosis and to differentiate significant fibrosis (F2–F4) from none to minimal fibrosis (F0–F1) in chronic hepatitis B (CHB). Liver biopsy results were mapped to an F0–4 equivalent fibrosis stage. Mean APRI and FIB-4 scores were significantly higher for each successive fibrosis level from F1 to F4 (P
Databáze:	OpenAIRE
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