Outcome of conservation surgery for laryngeal carcinoma: an 8-year trial
| Autor: | Rıza Dündar, Sedat Öztürkcan, Bilge Tuna, Yılmaz Özkul, Hüseyin Katilmiş, Filiz Gülistan, Ali Ekber Ilknur, Sinem Aktas |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Laryngectomy Cohort Studies medicine Carcinoma Humans Survival rate Laryngeal Neoplasms Aged Retrospective Studies business.industry Cancer Retrospective cohort study General Medicine Middle Aged medicine.disease Surgery Radiation therapy Survival Rate Treatment Outcome Otorhinolaryngology T-stage Radiotherapy Adjuvant Neurosurgery Neoplasm Recurrence Local business |
| Zdroj: | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 266(11) |
| ISSN: | 1434-4726 |
| Popis: | The purpose of this report is to review the experience of our institution with conservative surgery for laryngeal cancer. In this retrospective study, a review was made of 85 patients treated with conservation surgery between 1998 and 2005. At least 2 years of follow-up period (mean 46.6 months) was achieved for all the patients. We evaluated age, tobacco and alcohol intake, T stage, histopathological differentiation and localization of tumor, subglottic extension, anterior commissure invasion, vocal cord mobility, surgical margins, type of surgery applied, and post-operative radiotherapy (pRT) applied. Local control and 2-year survival rates were estimated. We managed with horizontal, vertical, and horizontovertical laryngectomies in 55, 26, and 4 patients, respectively. 28 patients were scheduled to have pRT. The actuarial and overall local control rates were 82.4 and 94.1%, respectively. On univariable analysis, significant factors for increased recurrences were positive resection margins, low differentiation of tumor, alcohol consumption and incompletion of the planned pRT. The 2-year survival rate was 60 and 95.7% for patients with and without local recurrence, respectively. Conservation surgery is a safe procedure for laryngeal cancer in proper endications. |
| Databáze: | OpenAIRE |
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