Morphological transformation of mouse embryo cells in vitro by murine sarcoma virus (Harvey)
| Autor: | D. E. H. Phillips, A. Turano, R. R. Dourmashkin, P. J. Simons, F. C. Chesterman |
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| Rok vydání: | 1967 |
| Předmět: |
viruses
Biology Stain Virus Morphological transformation chemistry.chemical_compound Mice Culture Techniques Animals Multidisciplinary Inoculation Murine sarcoma virus Acridine orange Embryo Embryo Mammalian Virology Molecular biology humanities In vitro Leukemia Virus Murine chemistry Microscopy Fluorescence Acridines sense organs Sarcoma Experimental Moloney murine leukemia virus |
| Zdroj: | Nature. 214(5091) |
| ISSN: | 0028-0836 |
| Popis: | Murine sarcoma virus (Harvey) produces characteristic changes in cultures of C57BL mouse embryo cells. Some of the cells become spindle-shaped and stain vividly with acridine orange. The transformed cells continuously produce virus in vitro and give tumours on inoculation into adult C57BL mice. The changes are similar to those produced by the Moloney strain of MSV. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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