In Vitro Bioaccessibility and Effect of Mangifera indica (Ataulfo) Leaf Extract on Induced Dyslipidemia
| Autor: | Juan A Gayosso de Lucio, José Arias-Rico, Raquel Cariño-Cortés, Mario I. Ortiz, Eli Mireya Sandoval-Gallegos, Esther Ramírez-Moreno, Nelly del Socorro Cruz-Cansino |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Drug Male DPPH media_common.quotation_subject Xanthones Medicine (miscellaneous) 01 natural sciences 03 medical and health sciences chemistry.chemical_compound Gallic Acid Medicine Animals Humans Mangifera Gallic acid Rats Wistar Mangiferin Triglycerides media_common Dyslipidemias Hypolipidemic Agents 030109 nutrition & dietetics Nutrition and Dietetics Traditional medicine business.industry Plant Extracts 010401 analytical chemistry Polyphenols medicine.disease Obesity 0104 chemical sciences Rats Plant Leaves Cholesterol chemistry Polyphenol business Dyslipidemia |
| Zdroj: | Journal of medicinal food. 21(1) |
| ISSN: | 1557-7600 |
| Popis: | Cardiovascular diseases (CVDs) are the leading causes of death in the world, and epidemiological evidence points to dietary habits, stress, and obesity as major risk factors promoting pathological conditions like atherosclerosis, hypertension, and thrombosis. Current therapeutic approaches for CVDs rely on lifestyle changes and/or the use of drug agents. However, since the efficacy of such interventions is often limited by poor compliance and/or significant side effects, continued research on new preventive and therapeutic approaches is much needed. Our study is aimed to determine the bioaccessibility, total content of phenolic compounds, and antioxidant capacity (DPPH·, ABTS·+) of a methanolic extract from Mangifera indica L. leaves (MEM), and its lipid-lowering effect on an induced dyslipidemia model in Wistar rats. Our results showed that mangiferin is the main component of MEM. The extract showed a total content of polyphenol compounds of 575.28 gallic acid equivalents per dry matter basis (G... |
| Databáze: | OpenAIRE |
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