Bladder carcinoma in Costello syndrome: Report on a patient born to consanguineous parents and review
| Autor: | Andrea Guala, D. Licata, Piergiorgio Franceschini, G. Di Cara, G. Ingrosso, D. Franceschini, M. Bianchi |
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| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Pediatrics Urinary bladder business.industry bladder carcinoma Costello syndrome Pediatric Tumor Consanguinity medicine.disease Malignancy Developmental disorder Increased risk medicine.anatomical_structure Endocrinology Costello syndrome Internal medicine medicine Carcinoma business Genetics (clinical) |
| Zdroj: | American Journal of Medical Genetics. 86:174-179 |
| ISSN: | 1096-8628 0148-7299 |
| Popis: | We report on a 12-year-old boy with Costello syndrome born to consanguineous (first cousins once removed) parents, supporting the hypothesis of recessive transmission of this syndrome. At age 11 years, the patient developed a bladder carcinoma, a rare pediatric tumor not previously described in Costello syndrome. This suggests that an increased risk of malignancy may be part of this condition. |
| Databáze: | OpenAIRE |
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