Symptomatic Primary Infection Due to Human Immunodeficiency Virus Type 1: Review of 31 Cases
| Autor: | B. Hirschel, P. De Saussure, S. Kinloch-de Loes, Jean-Hilaire Saurat, Luc Perrin, Hans Stalder |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Sexual transmission Physical examination HIV Infections Acquired immunodeficiency syndrome (AIDS) Risk Factors Internal medicine Immunopathology Epidemiology medicine Humans Sex organ Genitalia Skin Mouth medicine.diagnostic_test business.industry Middle Aged medicine.disease Rash Infectious Diseases Immunology HIV-1 Female Viral disease medicine.symptom business |
| Popis: | In this series of 31 patients with acute infection due to human immunodeficiency virus (HIV) type 1, the male-to-female ratio was 3.4:1 and the mean age was 31.3 years. Sexual transmission accounted for 83.9% of cases; 45.2% of the patients were homosexual and 38.7% were heterosexual. The mean duration of symptoms and signs was 21 days (range, 5-60 days). Fever (87.1%) and skin rash (67.7%) were most commonly reported. Physical examination findings were abnormal for 96% of the patients; the oral cavity (76.7%) and the skin (73.3%) were the most frequently involved sites. Thirteen of 25 patients with sexually acquired infection had genital or oral ulcers, whereas five intravenous drug users had none (P = .052). Thrombocytopenia was the most common hematologic abnormality and was detected in 17 of 23 patients tested. P24 antigenemia, an initially negative screening test for HIV antibody, and a low CD4+ lymphocyte count were noted in 23 of 29, 23 of 30, and 14 of 21 tested patients, respectively. |
| Databáze: | OpenAIRE |
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