An experimental ovine foot abscess model using a Fusobacterium necrophorum biotype AB
| Autor: | N.D. Collins, Vaughan Ja, Leigh A. L. Corner |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
Pathology medicine.medical_specialty ved/biology.organism_classification_rank.species Foot abscess Sheep Diseases Biology Microbiology Fusobacterium necrophorum medicine Animals Abscess Bacteroidaceae Foot Dermatoses Sheep General Veterinary ved/biology Inoculation General Medicine medicine.disease biology.organism_classification Fusobacterium Fusobacterium Infections Foot (unit) Bacteria |
| Zdroj: | Veterinary microbiology. 48(1-2) |
| ISSN: | 0378-1135 |
| Popis: | An experimental procedure is described for the production of foot abscess in sheep that mimics the natural disease. Lesions were produced by the intradermal inoculation of suspensions of Fusobacterium necrophorum biotype AB containing from 5 × 10 2 to 5 × 10 8 bacteria, into interdigital skin devitalised by freezing with liquid nitrogen. A dose of 5 × 10 5 bacteria induced the development of foot abscess in 3 of 4 and 8 of 8 inoculated feet. It was found that to produce foot abscess in devitalised tissue required between 10 3 and 10 6 fewer bacteria than were necessary to produce similar lesions in healthy tissue. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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