Hand-foot syndrome and its impact on daily activities in breast cancer patients receiving docetaxel-based chemotherapy

Autor: Yu-Fen Lin, Chao-Hui Wang, Wen-Chi Shen, Ya-Hui Hsu, Shu-Ching Chen
Rok vydání: 2019
Předmět:
Zdroj: European Journal of Oncology Nursing. 43:101670
ISSN: 1462-3889
DOI: 10.1016/j.ejon.2019.09.011
Popis: Purpose Breast cancer patients who undergo docetaxel-based chemotherapy regimens can have hand-foot syndrome (HFS), which negatively impacts their ability to perform daily activities. The purpose of the study was to assess, in breast cancer patients receiving chemotherapy: the perceived levels of HFS-related symptoms of the feet, hands or fingers; and HFS-related restrictions in daily activities; as well as to identify factors associated with these symptoms and restrictions. Methods This cross-sectional study examined breast cancer patients who received docetaxel-based chemotherapy from the general surgery outpatient department and oncology outpatient department of a medical center in northern Taiwan. A set of structured questionnaires were used to measure patients’ HFS-related symptoms and HFS-related restrictions in daily activities. Results Of the 85 breast cancer patients studied, 41.2% reported HFS. Patients had higher level of HFS-related foot symptoms than HFS-related hand or fingers symptoms. Greater restriction in HFS-related daily activities was associated with more HFS-related hand or fingers symptoms and more HFS-related foot symptoms; these factors explained 44.7% of the variance in restriction of activities. Conclusion Skin care and patient education should be provided to manage the HFS of breast cancer patients receiving chemotherapy.
Databáze: OpenAIRE