Periventricular Echodensity Measured with the Integrated Backscatter System: From a Qualitative Assessment to a Quantitative Approach
| Autor: | Kenichi Tokuyama, Yasushi Ohki, Yukiko Takahashi, Masayuki Watanabe, Yukihiro Yoshizawa, Hiroo Mayuzumi, Akihiro Morikawa |
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| Rok vydání: | 2009 |
| Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Leukomalacia Periventricular Gestational Age Periventricular white matter Cerebral Ventricles Image Processing Computer-Assisted Birth Weight Humans Medicine cardiovascular diseases Integrated backscatter reproductive and urinary physiology Periventricular leukomalacia medicine.diagnostic_test business.industry Obstetrics Infant Newborn medicine.disease Echoencephalography nervous system diseases nervous system Infant Extremely Low Birth Weight Calibration Choroid Plexus Pediatrics Perinatology and Child Health Female Radiology Ultrasonography business Developmental Biology |
| Zdroj: | Neonatology. 96:219-225 |
| ISSN: | 1661-7819 1661-7800 |
| DOI: | 10.1159/000215592 |
| Popis: | Background: The degree of periventricular white matter echodensity in preterm infants has been utilized as a sign of the early ultrasonographic appearance of periventricular leukomalacia, and this has been called periventricular echodensity (PVE). Objectives: The aim of this study was to quantitatively measure PVE utilizing a new method which is called calibrated integrated backscatter (calibrated IB). Methods: Eighty-eight preterm infants (extremely low birth weight infants, n = 17; very low birth weight infants, n = 26; low birth weight infants, n = 45) without any CNS abnormality were enrolled. IB is the returned sound pressure against supersonic waves sent from an ultrasonographic machine. The IB of the choroid plexus and periventricular white matter in the subrolandic area were measured on a parasagittal cerebral image. The degree of PVE was defined by subtracting the IB of the choroid plexus from that of the periventricular white matter in the subrolandic area (calibrated IB of PVE). Results: The intraobserver and interobserver correlations were both excellent (between 0.87 and 0.98 as correlation coefficients). There was a trend for the calibrated IB of PVE to decrease in accordance with time after birth, with a significant difference in very low birth weight and low birth weight infants. Conclusions: The objectively measured brightness of PVE was comparable to that of the choroid plexus irrespective of the size of the infants. Measurement of the calibrated IB of PVE might be a reliable method to assess PVE. |
| Databáze: | OpenAIRE |
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