Age-grouped differences in bipolar mania
| Autor: | Daniel J. Safer, Alan M. Safer, Julie M. Zito |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Male
Bipolar Disorder Psychometrics Aripiprazole Comorbidity Anger Quinolones Piperazines Thinking Benzodiazepines lcsh:Psychiatry Child Defense Mechanisms Clinical Trials as Topic Not Otherwise Specified Age Factors Middle Aged Irritable Mood Aggression Psychiatry and Mental health Clinical Psychology Attention Deficit and Disruptive Behavior Disorders Olanzapine Female medicine.symptom Mania Antipsychotic Agents medicine.drug Clinical psychology Adult medicine.medical_specialty Adolescent lcsh:RC435-571 Sexual Behavior Motor Activity Irritability Young Mania Rating Scale behavioral disciplines and activities Young Adult Rating scale mental disorders medicine Humans Bipolar disorder Psychiatry Psychiatric Status Rating Scales business.industry medicine.disease business |
| Zdroj: | Comprehensive Psychiatry, Vol 53, Iss 8, Pp 1110-1117 (2012) |
| ISSN: | 0010-440X |
| DOI: | 10.1016/j.comppsych.2012.04.011 |
| Popis: | Objective This review of published studies compares scores on individual items of mania rating scales that systematically recorded symptom severity in persons diagnosed with bipolar disorder to identify age-grouped differences. Methods An extensive literature search identified item scores from mania rating scales, with a particular emphasis on baseline Young Mania Rating Scale (YMRS) item scores in published double-blind, placebo-controlled studies of bipolar I manic disorder. These baseline YMRS item scores were assessed as a proportion of the total YMRS score and compared by age group. Additional YMRS item/total scores in subjects with bipolar spectrum disorders were added to expand the analysis. Results Preadolescents with bipolar disorder had significantly higher YMRS item scores than adolescents on aggression, irritability, and motor activity. Young Mania Rating Scale baseline item scores relative to the YMRS total score revealed that adolescents diagnosed with bipolar I mania scored comparatively higher than did adults on YMRS aggression and irritability items, whereas adults with bipolar I manic disorder scored comparatively higher on the grandiosity and sexual interest items. Age-grouped findings from subjects diagnosed with bipolar I, II, and Not Otherwise Specified (NOS) disorders yielded similar age-grouped results. Conclusion In age-grouped YMRS item assessments of bipolar mania, anger dyscontrol was most prominent for youth, whereas disordered thought content was paramount for adults. |
| Databáze: | OpenAIRE |
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