Chromosome Translocation in Residents of the High Background Radiation Areas in Southern China
| Autor: | Hiroshige Morishima, Masako Minamihisamatsu, Deqing Chen, Wei Zhang, Tsutomu Sugahara, Isamu Hayata, Chunyan Wang, Luxin Wei, Yongling Yuan |
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| Rok vydání: | 2000 |
| Předmět: |
Male
China Health Toxicology and Mutagenesis Physiology Chromosomal translocation Biology Chromosomes Translocation Genetic Chromosome Painting Quartz fiber dosimeter Background Radiation Humans Dose effect Radiology Nuclear Medicine and imaging Chromosome painting analysis Child Radiometry Aged Congenital diseases Radiation business.industry Potential risk Chromosome Middle Aged Southern china Nuclear medicine business |
| Zdroj: | Journal of Radiation Research. 41:69-74 |
| ISSN: | 1349-9157 0449-3060 |
| Popis: | We performed a cytogenetical study using chromosome painting analysis on 9 residents of the naturally high background radiation areas (HBRA) and 8 residents of the control areas in southern China. The estimated dose (air kerma) of each resident measured by an electric pocket dosimeter showed 2.20-4.23 mGy/year in HBRA and 0.56-0.70 mGy/year in the control areas. A total of 14,096 cells (1,566 cells/case) in the former and 17,522 cells (2,190 cells/case) in the latter were analyzed. Children, both in HBRA and in the control areas, had translocations at low frequencies. The frequency of translocations among elder individuals varied widely and it was not possible to detect dose effect although it was detected in dicentrics. The effect of radiation on the induction of chromosome aberrations, which have a statistically potential risk of causing malignant or congenital diseases, seems to be less significant than those of metabolic factors and/or mutagenic agents (excluding radiation) even in HBRA in China. |
| Databáze: | OpenAIRE |
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