A Comparison of Nephrotoxicity of Contrast Medium in Elderly Patients who Underwent Renal or Peripheral Arterial Vascular Intervention
| Autor: | Lei Song, Yubao Zou, Yuejin Yang, Hui Dong, Xiongjing Jiang, Haiying Wu, Runlin Gao, Huimin Zhang, Meng Peng |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Urology Contrast-induced nephropathy Contrast Media Renal function Arterial Occlusive Diseases 030204 cardiovascular system & hematology Coronary Angiography Kidney Function Tests 030218 nuclear medicine & medical imaging Nephropathy Nephrotoxicity 03 medical and health sciences chemistry.chemical_compound Renal Artery 0302 clinical medicine Risk Factors Triiodobenzoic Acids Internal Medicine medicine Humans Prospective Studies Renal Insufficiency Prospective cohort study Aged Aged 80 and over Creatinine business.industry General Medicine Odds ratio medicine.disease Iodixanol Surgery chemistry Female business Follow-Up Studies medicine.drug |
| Zdroj: | Internal Medicine. 55:9-14 |
| ISSN: | 1349-7235 0918-2918 |
| Popis: | Objective To compare the nephrotoxicity of iodixanol in elderly patients who underwent a renal artery intervention (RAI) with those who underwent an other peripheral vascular intervention (OPI). Methods Three hundred fifty-four consecutive patients (g60 years old) received iodixanol during RAI (n=150) or OPI (n=204). The level of serum creatinine (SCr) was measured at the baseline, 24 hours, 48 hours, 72 hours and 1 month after intervention. Results Within 72 hours after the intervention, the adjusted mean of the peak SCr increase was 11.22 umol/L 〔95% confidence interval (CI): 9.21-13.24〕 in the RAI group and 12.40 umol/L (95%CI: 10.7-14.09) in the OPI group. The difference in the peak SCr increase was -1.17 umol/L (95%CI: -3.94-1.60; p=0.406). Contrast-induced nephropathy occurred in 26 patients (17.3%) of the RAI group and in 27 patients (13.2%) of the OPI group (p=0.286). Patients who underwent an RAI showed no increased risk for contrast-induced nephropathy in comparison with patients who underwent an OPI 〔adjusted odds ratio (OR)=1.108; 95%CI: 0.540-2.273; p=0.780〕. Conclusion The nephrotoxic effect of iodixanol in elderly patients who underwent RAI or OPI was comparable. |
| Databáze: | OpenAIRE |
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