Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes against Mycobacterium tuberculosis
| Autor: | Bapu R. Thorat, Ramesh S. Yamgar, Dnyaneshwar Shelke, Mustapha C. Mandewale |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
biology Article Subject Stereochemistry lcsh:Biotechnology Organic Chemistry Quinoline Hydrazone biology.organism_classification Biochemistry Fluorescence lcsh:QD146-197 Inorganic Chemistry Mycobacterium tuberculosis Metal chemistry.chemical_compound chemistry visual_art Biological property lcsh:TP248.13-248.65 visual_art.visual_art_medium lcsh:Inorganic chemistry Biological evaluation Nuclear chemistry Research Article |
| Zdroj: | Bioinorganic Chemistry and Applications, Vol 2015 (2015) Bioinorganic Chemistry and Applications |
| ISSN: | 1565-3633 |
| Popis: | A new series of quinoline hydrazone derivatives and their metal complexes have been synthesized and their biological properties have been evaluated againstMycobacterium tuberculosis(H37 RV strain). Most of the newly synthesized compounds displayed 100% inhibitory activity at a concentration of 6.25–25 μg/mL, againstMycobacterium tuberculosis. Fluorescence properties of all the synthesized compounds have been studied. |
| Databáze: | OpenAIRE |
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