Delineating the critical role of acid additives in Mn-catalysed C–H bond functionalisation processes
| Autor: | L. Anders Hammarback, Alan Robinson, Jason M. Lynam, Ian J. S. Fairlamb |
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| Rok vydání: | 2019 |
| Předmět: |
C h bond
010405 organic chemistry Chemistry ved/biology ved/biology.organism_classification_rank.species Metals and Alloys chemistry.chemical_element General Chemistry Manganese 010402 general chemistry 01 natural sciences Medicinal chemistry Catalysis 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Materials Chemistry Ceramics and Composites Conjugate acid Catalyst degradation |
| Zdroj: | Chemical Communications. 55:3211-3214 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c9cc00257j |
| Popis: | Addition of co-catalytic Cy2NH to Mn-catalysed C-H bond activation reactions suggests that the conjugate acid, Cy2NH2X, influences catalysis. Here, acids are shown to positively influence C-H bond alkenylation catalysis involving alkynes. For certain types of alkynes an acid additive is critical to catalysis. In stark contrast, acids retard catalysis involving acrylates. [Cy2NH2]X salts also play a key role in thwarting catalyst degradation to manganese clusters. Our findings enable unreactive substrates to be alkenylated. |
| Databáze: | OpenAIRE |
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