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Covid-19, what a strange, unpredictable mutated virus. It has baffled many scientists, as no firm rule has yet been reached to predict the effect that the virus can inflict on people if they are infected with it. Recently, many researches have been introduced for diagnosing Covid-19; however, none of them pay attention to predict the effect of the virus on the person's body if the infection occurs but before the infection really takes place. Predicting the extent to which people will be affected if they are infected with the virus allows for some drastic precautions to be taken for those who will suffer from serious complications, while allowing some freedom for those who expect not to be affected badly. This paper introduces Covid-19 Prudential Expectation Strategy (CPES) as a new strategy for predicting the behavior of the person's body if he has been infected with Covid-19. The CPES composes of three phases called Outlier Rejection Phase (ORP), Feature Selection Phase (FSP), and Classification Phase (CP). For enhancing the classification accuracy in CP, CPES employs two proposed techniques for outlier rejection in ORP and feature selection in FSP, which are called Hybrid Outlier Rejection (HOR) method and Improved Binary Genetic Algorithm (IBGA) method respectively. In ORP, HOR rejects outliers in the training data using a hybrid method that combines standard division and Binary Gray Wolf Optimization (BGWO) method. On the other hand, in FSP, IBGA as a hybrid method selects the most useful features for the prediction process. IBGA includes Fisher Score (F |