Optimal control of type 1 diabetes mellitus in youth receiving intensive treatment
| Autor: | Miranda Vincent, Dena Springer, James Dziura, Amy T. Steffen, Joann Ahern, Stuart A. Weinzimer, William V. Tamborlane |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty endocrine system diseases Injections Subcutaneous medicine.medical_treatment Ethnic group Insulin Infusion Systems Internal medicine Diabetes mellitus Ethnicity medicine Humans Hypoglycemic Agents Insulin Child Socioeconomic status Glycemic Glycated Hemoglobin Type 1 diabetes business.industry nutritional and metabolic diseases medicine.disease Surgery Diabetes Mellitus Type 1 Treatment Outcome Socioeconomic Factors Metabolic control analysis Pediatrics Perinatology and Child Health Female business Body mass index |
| Zdroj: | The Journal of Pediatrics. 149:227-232 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/j.jpeds.2006.03.052 |
| Popis: | To investigate the impact of factors that might interfere with optimal glycemic control in youth with type 1 diabetes mellitus (T1DM) in the current era of intensive management, including the interplay of race/ethnicity and socioeconomic status (SES) on HbA1c levels.This study comprised a database review of all patients under age 18 years with T1DM for at least 6 months duration. Sex, age, race/ethnicity, duration of diabetes, mode of insulin administration (pump vs injection), body mass index, SES, and HbA1c level were recorded at each patient's most recent visit between January and September 2003.Mean HbA1c level for the 455 patients was 7.6% +/- 1.4%; only 31% of patients failed to meet the therapeutic goal of8.0%. Multiple linear regression analysis identified female sex (P = .02), older age (P = .001), longer duration of diabetes (P.001), injection therapy (P.001), and lower SES (P = .001) as significantly associated with higher HbA1c level. After adjustment for SES, race/ethnicity was not a determinant of HbA1c level.Low SES had a greater association with poor metabolic control than did race/ethnicity, which was not associated with differences in HbA1c level after controlling for SES. Most children were able to attain glycemic targets at least as good as the Diabetes Control and Complications Trial recommendations in a large clinical practice. |
| Databáze: | OpenAIRE |
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