The best way to assess oedema using T1, T2 mapping or three-dimensional T2-weighted fast-spin-echo triple inversion recovery sequences via cardiovascular MRI in outpatients with suspected myocarditis
| Autor: | Simone Kimmel, S. von Rauffer, M. Jeserich, Stephan Achenbach, P. Maisch |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Myocarditis T2 mapping Contrast Media Inversion recovery 030218 nuclear medicine & medical imaging 03 medical and health sciences Imaging Three-Dimensional Meglumine 0302 clinical medicine Text mining Image Interpretation Computer-Assisted Outpatients Organometallic Compounds Edema Humans Medicine Radiology Nuclear Medicine and imaging In patient Prospective Studies business.industry General Medicine Middle Aged Fast spin echo medicine.disease Magnetic Resonance Imaging Case-Control Studies 030220 oncology & carcinogenesis Inferior wall Female business T2 weighted Nuclear medicine |
| Zdroj: | Clinical Radiology. 75:383-389 |
| ISSN: | 0009-9260 |
| DOI: | 10.1016/j.crad.2020.01.006 |
| Popis: | AIM To evaluated T1-, T2 mapping, and a three-dimensional (3D) T2-weighted fast-spin-echo triple inversion recovery sequences (3D STIR) for diagnosing myocardial oedema in patients with suspected early myocarditis and at follow-up. MATERIALS AND METHODS Sixteen patients with suspected myocarditis and 15 controls matched for gender and age were examined prospectively. To evaluate oedema, an electrocardiogram-triggered T1 and T2 mapping with a gradient spin echo technique and 3D STIR sequences were used to cover the entire left ventricle. The signal intensity ratio (heart muscle in relation to skeletal muscle) was calculated (3D STIR ratio). All patients underwent repeat examinations at follow-up. RESULTS The mean 3D-STIR ratio was 2.14±0.45 at the patients' initial examination as compared to the control patients' 1.54±0.18 in (p=0.0001) and 1.75±0.16 in patients at follow-up (p=0.002 versus first visit). The 3D STIR ratio of the septum, anterior, lateral, and inferior wall also differed significantly between patients and controls. No significant difference was observed in T1 and T2 mapping between patients and controls at baseline and patients at follow-up. CONCLUSIONS A significantly higher global signal intensity ratio with 3D-STIR was identified in patients with suspected myocarditis compared to controls, and a significant change during follow-up. No significant difference was detected in T1-, T2 mapping between patients and controls, or between the initial examination and follow-up of patients. The global 3D-STIR ratio may therefore be useful for the diagnosis of myocarditis and should be explored further. |
| Databáze: | OpenAIRE |
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