Evolution of body composition and wasting indicators by time of day of haemodialysis
| Autor: | Bernard Canaud, Adam M Zawada, Stefano Stuard, Adelheid Gauly, Denis Fouque, Juan Jesus Carrero, Melanie Wolf, Anke Winter |
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| Přispěvatelé: | Registry of the European Renal Association − European Dialysis and Transplant Association. (ERA-EDTA Registry ), Karolinska Institutet [Stockholm], Fresenius Medical Care [Bad Homburg], Université de Montpellier (UM), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CarMeN, laboratoire, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier) |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty dialysis shift [SDV]Life Sciences [q-bio] medicine.medical_treatment 030232 urology & nephrology Nutritional Status 030204 cardiovascular system & hematology Protein-Energy Malnutrition Gastroenterology Body Mass Index Cachexia 03 medical and health sciences chemistry.chemical_compound fat tissue index 0302 clinical medicine Renal Dialysis Internal medicine medicine Humans Wasting Dialysis Aged Retrospective Studies Morning 2. Zero hunger body composition Transplantation Creatinine Meal business.industry Middle Aged medicine.disease [SDV] Life Sciences [q-bio] Adipose Tissue chemistry Nephrology protein-energy wasting Female Hemodialysis lean tissue index medicine.symptom business Body mass index |
| Zdroj: | Nephrology Dialysis Transplantation Nephrology Dialysis Transplantation, Oxford University Press (OUP), 2021, 36 (2), pp.346-354. ⟨10.1093/ndt/gfaa253⟩ Nephrology Dialysis Transplantation, 2021, 36 (2), pp.346-354. ⟨10.1093/ndt/gfaa253⟩ |
| ISSN: | 1460-2385 0931-0509 |
| DOI: | 10.1093/ndt/gfaa253 |
| Popis: | Background It has been a long-standing clinical concern that haemodialysis (HD) patients on afternoon shifts (ASs) are more prone to protein-energy wasting (PEW) than those on morning shifts (MSs), as their dialysis scheme and post-dialysis symptoms may interfere with meal intake. We evaluated the effect of time of day of HD on the evolution of body composition changes and PEW surrogates. Methods We conducted a retrospective study among 9.963 incident HD patients treated in NephroCare centres (2011–16); data were routinely collected in the European Clinical Database. The course of multi-frequency bioimpedance determined lean and fat tissue indices (LTI and FTI) between patients in MSs/ASs over 2 years were compared with linear mixed models. Secondary PEW indicators were body mass index, albumin, creatinine index and normalized protein catabolic rate. Models included fixed (age, sex, vascular access and diabetes mellitus) and random effects (country and patient). Results Mean baseline LTI and FTI were comparable between MSs (LTI: 12.5 ± 2.9 kg/m2 and FTI: 13.7 ± 6.0 kg/m2) and ASs (LTI: 12.4 ± 2.9 kg/m2 and FTI: 13.2 ± 6.1 kg/m2). During follow-up, LTI decreased and FTI increased similarly, with a mean absolute change (baseline to 24 months) of −0.3 kg/m2 for LTI and +1.0 kg/m2 for FTI. The course of these malnutrition indicators did not differ between dialysis shifts (P for interaction ≥0.10). We also did not observe differences between groups for secondary PEW indicators. Conclusions This study suggests that a dialysis shift in the morning or in the afternoon does not impact the long-term nutritional status of HD patients. Regardless of time of day of HD, patients progressively lose muscle mass and increase body fat. |
| Databáze: | OpenAIRE |
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