Role of Whole-Body Staging Computed Tomographic Scans for Detecting Distant Metastases in Patients With Bladder Cancer
| Autor: | Rachael Fung, Kevin Mulcahy, Heminder Sokhi, Arumugam Rajesh, Michael J.G. Bankart |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Whole body imaging Contrast Media Metastasis symbols.namesake medicine Carcinoma Humans Neoplasm Invasiveness Whole Body Imaging Radiology Nuclear Medicine and imaging Fisher's exact test Aged Neoplasm Staging Retrospective Studies Aged 80 and over Carcinoma Transitional Cell Bladder cancer business.industry Incidence Retrospective cohort study Odds ratio Middle Aged medicine.disease Iopamidol Logistic Models Transitional cell carcinoma Urinary Bladder Neoplasms symbols Female Radiology Tomography X-Ray Computed business |
| Zdroj: | Journal of Computer Assisted Tomography. 35:402-405 |
| ISSN: | 0363-8715 |
| Popis: | Objective This study aimed to establish the incidence of distant metastases on whole-body computed tomographic (CT) scans in patients with newly diagnosed bladder cancer and to determine whether there is a significant difference in the incidence of metastases in patients with superficial and muscle invasive cancers. Materials and methods A total of 201 patients who had a proven histological diagnosis of transitional cell carcinoma of the bladder and a whole-body staging CT scan at diagnosis were identified from our MDT database during a 36-month period. Imaging was retrospectively reviewed with view to recording site, if any, of distant metastases. Results Of 201 patients, 11 (5.5%) were found to have distant metastases on CT. In univariable models, staging was not associated with either age (odds ratio, 0.98; 95% confidence interval, 0.92-1.04; P = 0.4) or sex (Fisher exact test, P = 0.07). Mean (SD) age was 74.1 (10.5) years. There was a significant association between staging and metastasis (odds ratio, 19.9; 95% confidence interval, 3.2-infinity; P = 0.0003). Of the patients, 7% of males had metastases versus 0% of the females. Conclusions Staging CT scans for assessment of distant metastatic disease in patients with newly diagnosed bladder cancer can be restricted to patients with muscle invasive disease. |
| Databáze: | OpenAIRE |
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