Non-small cell lung cancer with the tracheal bifurcation involvement. Carinal pneumonectomy or chemo-radiation therapy?
| Autor: | M M Davydov, M A Ibraev, Amir G. Abdullaev, A A Filatov, M S Shogenov, I A Dadyev |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Cancer Research
medicine.medical_specialty business.industry medicine.medical_treatment locally advanced lung cancer lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease lcsh:RC254-282 Chemo radiation Resection Surgery Pneumonectomy pneumonectomy with resection of the tracheal bifurcation radical chemo-radiation therapy Oncology medicine Tracheal bifurcation Non small cell Statistical processing Lung cancer business circular resection of the tracheal bifurcation Survival rate |
| Zdroj: | Современная онкология, Vol 20, Iss 4, Pp 32-35 (2018) |
| ISSN: | 1815-1442 1815-1434 |
| DOI: | 10.26442/18151434.2018.4.180161 |
| Popis: | The aim of the study: the aim of this study was to compare the immediate and long-term results of treatment of patients with non-small cell lung cancer with involvement of tracheal bifurcation, which were underwent pneumonectomy with resection of the tracheal bifurcation or radical chemo-radiation therapy (CRT). Materials and methods. We conducted a retrospective non-randomized clinical study with following groups of patients: 1) 65 patients who underwent pneumonectomy with resection of the tracheal bifurcation; 2) 30 patients to whom CRT was performed. Evaluation of the effectiveness of immediate and long-term results was carried out by statistical processing using the Statistic 6.0 program. A case-control analysis was performed to compare two groups. The time of the operation, intra- and postoperative complications was estimated depending on the type of resection of the tracheal bifurcation. Results. The complication rate was 46.1% in the surgical group. In the CRT group complications developed in 13 (43.3%) patients. The overall 1-, 3-, 5-year survival rate in the group of patients with surgical treatment was 56.92, 31.7 and 26.1%, respectively. The median overall survival was 14.5 months. Indicators of 1-, 3-, and 5-year survival in the group of patients who underwent radical CRT were 31.6, 24.4, 16.2%. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|