Neuroblastoma in an adult: Case report

Autor: Priscila Bernardina Miranda Soares, William Pereira de Souza, Paulo Rogério Ferreti Bonan, Sidnei Quirino Filho, Hercílio Martelli-Júnior
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Revista médica de Chile v.138 n.9 2010
SciELO Chile
CONICYT Chile
instacron:CONICYT
Popis: Neuroblastoma is the most common extracranial solid malignancy in children but rarely described in adults, being 10% of all cases diagnosed after the first decade of life. We report a 23 year-old black woman with a mass at paravertebral region of T3-T5, multiple lesions in vertebral bodies and expanding skull-brain lesion at the right parietal region. Immunohistochemical analysis (negative for CD99, CD20, CD3 and desmin; and positive chromogranin, synaptophysin and NB84) confi rmed the diagnosis of neuroblastoma. The patient was submitted to 12 cycles of chemotherapy receiving VAC (vincristine/doxorubicin/cyclophosphamide) interspersed with ICE (ifosfamide/mesna/etoposide) and doxorubicin was replaced by actinomycin in the 7th cycle. She had good tolerance to this therapy, and has been clinically stable.
Databáze: OpenAIRE