Neuroblastoma in an adult: Case report
| Autor: | Priscila Bernardina Miranda Soares, William Pereira de Souza, Paulo Rogério Ferreti Bonan, Sidnei Quirino Filho, Hercílio Martelli-Júnior |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Biopsy Bone Neoplasms Thoracic Vertebrae Carboplatin Young Adult Neuroblastoma Drug Therapy Neoplasms Antineoplastic Combined Chemotherapy Protocols Humans Medicine Ifosfamide Spinal Cord Neoplasms Antineoplastic protocols Cyclophosphamide Etoposide Mesna Gynecology Brain Neoplasms business.industry Adult case General Medicine medicine.disease Doxorubicin Vincristine Female business Spinal Cord Compression |
| Zdroj: | Revista médica de Chile v.138 n.9 2010 SciELO Chile CONICYT Chile instacron:CONICYT |
| Popis: | Neuroblastoma is the most common extracranial solid malignancy in children but rarely described in adults, being 10% of all cases diagnosed after the first decade of life. We report a 23 year-old black woman with a mass at paravertebral region of T3-T5, multiple lesions in vertebral bodies and expanding skull-brain lesion at the right parietal region. Immunohistochemical analysis (negative for CD99, CD20, CD3 and desmin; and positive chromogranin, synaptophysin and NB84) confi rmed the diagnosis of neuroblastoma. The patient was submitted to 12 cycles of chemotherapy receiving VAC (vincristine/doxorubicin/cyclophosphamide) interspersed with ICE (ifosfamide/mesna/etoposide) and doxorubicin was replaced by actinomycin in the 7th cycle. She had good tolerance to this therapy, and has been clinically stable. |
| Databáze: | OpenAIRE |
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