Tumor necrosis factor-α soluble receptor p55 (sTNFp55) and risk of preeclampsia in Peruvian women

Autor: Cuilin Zhang, Víctor Bazul, Gloria Larrabure, Suzie Ware-Jauregui, Michelle A. Williams, Sixto E. Sanchez, Allen Farrand
Rok vydání: 2000
Předmět:
Zdroj: Journal of Reproductive Immunology. 47:49-63
ISSN: 0165-0378
DOI: 10.1016/s0165-0378(99)00064-9
Popis: We conducted a large case-control study to assess the risk of preeclampsia with elevated sTNFp55 concentrations (markers of excessive TNF-alpha release) in Peruvian women. A total of 125 women with preeclampsia and 179 normotensive women were included in a study conducted during the period, June 1997 through January 1998. Antepartum (third-trimester) plasma sTNFp55 was measured by enzyme linked immunosorbent assay. Mean plasma sTNFp55 concentrations were 32.4% higher among preeclampsia cases (920.1+/-30.4 pg/ml) as compared with controls (694.8+/-15.0 pg/ml, Student's t-test P
Databáze: OpenAIRE