Effect of breathing rate on oxygen saturation and exercise performance in chronic heart failure

Autor:	Jerzy Bellwon, Axel W. Frey, Ramiz Hajric, Luciano Bernardi, Giammario Spadacini, Helmut Roskamm
Rok vydání:	1998
Předmět:	Male Respiratory Therapy medicine.medical_specialty Respiratory rate Ventilation/perfusion ratio Pulmonary function testing Internal medicine Ventilation-Perfusion Ratio medicine Humans Respiratory system Heart Failure Pulmonary Gas Exchange business.industry Respiration Respiratory disease General Medicine Middle Aged medicine.disease Surgery Oxygen Dyspnea Heart failure Exercise Test Cardiology Breathing Female business Respiratory minute volume
Zdroj:	The Lancet. 351:1308-1311
ISSN:	0140-6736
DOI:	10.1016/s0140-6736(97)10341-5
Popis:	In chronic heart failure (CHF), impaired pulmonary function can independently contribute to oxygen desaturation and reduced physical activity. We investigated the effect of breathing rate on oxygen saturation and other respiratory indices.Arterial oxygen saturation (SaO2) and respiratory indices were recorded during spontaneous breathing (baseline) and during controlled breathing at 15, six, and three breaths per min in 50 patients with CHF and in 11 healthy volunteers (controls). 15 patients with CHF were randomly allocated 1 month of respiratory training to decrease their respiratory rate to six breaths per min. Respiratory indices were recorded before training, at the end of training, and 1 month after training.During spontaneous breathing, mean SaO2 was lower in CHF patients than in controls (91-4% [SD 0.4] vs 95.4% [0.2], p0.001). Controlled breathing increased SaO2 at all breathing rates in patients with CHF. Compared with baseline, minute ventilation increased at 15 breaths per min (+45.9% [9.8], p0.01), did not change at six breaths per min, and decreased at three breaths per min (-40.3% [4.8], p0.001). In the nine CHF patients who had 1 month of respiratory training, resting SaO2 increased from 92.5% (0.3) at baseline to 93.2% (0.4) (p0.05), their breathing rate per min decreased from 13.4 (1.5) to 7.6 (1.9) (p0.001), peak oxygen consumption increased from 1157 (83) to 1368 (110) L/min (p0.05), exercise time increased from 583 (29) to 615 (23) min/s (p0.05), and perception of dyspnoea reduced from a score of 19.0 (0.4) to 17.3 (0.9) on the Borg scale (p0.05). There were no changes in the respiratory indices in the patients who did not have respiratory training.Slowing respiratory rate reduces dyspnoea and improves both resting pulmonary gas exchange and exercise performance in patients with CHF.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affa9a8c555c9267c805a667ffa7cb25 https://doi.org/10.1016/s0140-6736(97)10341-5 Zobrazit plný text záznamu Plný text ve formátu HTML
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