Short-course high-dose ibuprofen causing both early and delayed jejunal perforations in a non-smoking man
| Autor: | Aseef Yehiyan, Sowrav Barman, Haren Varia, Stephen Pettit |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Abdominal pain Time Factors Images In… medicine.medical_treatment Peritonitis Ibuprofen Jejunum 03 medical and health sciences 0302 clinical medicine Laparotomy medicine Back pain Humans Stomach Ulcer Omeprazole business.industry Anti-Inflammatory Agents Non-Steroidal Jejunal Diseases General Medicine Middle Aged medicine.disease Abdominal Pain Surgery Treatment Outcome medicine.anatomical_structure Back Pain Intestinal Perforation 030211 gastroenterology & hepatology medicine.symptom Vasculitis business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | BMJ Case Reports. :bcr-2017 |
| ISSN: | 1757-790X |
| Popis: | A 48-year-old non-smoking man underwent laparotomy for peritonitis immediately after taking ibuprofen 800 mg 6 hourly for 14 days for back pain. His only other medication was long-term omeprazole 20 mg per day. At operation he had three separate perforations in his proximal jejunum. Fifteen centimetres of jejunum were resected with primary anastomosis. Histology showed focal mucosal ischaemic changes with normal mucosa between. There was no vasculitis. The perforations were attributed to ibuprofen intake. He made an uneventful recovery and was instructed to refrain from non-steroidal anti-inflammatory drug (NSAID) intake. He was readmitted … |
| Databáze: | OpenAIRE |
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