Strategic vaccination of hair sheep against Haemonchus contortus
| Autor: | Antônio Francisco Igor Magalhães Matos, Marcel Teixeira, César Cristiano Bassetto, J. P. Monteiro, W. D. Smith, Fernando Henrique Melo Andrade Rodrigues de Albuquerque |
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| Přispěvatelé: | Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA), Centro Universitário UNINTA, Universidade Estadual Vale do Acarau, Universidade Federal de Santa Maria, Universidade Estadual Paulista (Unesp), Pentlands Science Park |
| Rok vydání: | 2018 |
| Předmět: |
Veterinary medicine
medicine.medical_specialty Antibodies Helminth Sheep Diseases Medical microbiology Antigen Control parasitic diseases medicine Animals Anthelmintic Parasite Egg Count Management practices Nematode Vaccines Sheep General Veterinary biology Vaccination General Medicine biology.organism_classification Infectious Diseases Insect Science Parasitology Female Haemonchus Infection Blood parameters Haemonchiasis Haemonchus contortus medicine.drug |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 1432-1955 |
| Popis: | Made available in DSpace on 2019-10-06T15:47:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-01 In this study, we evaluated in two trials a protocol designed to protect hair sheep using Barbervax®, a vaccine containing Haemonchus contortus gut membrane glycoprotein antigens. Results indicated that naturally infected vaccinated sheep had significant egg count reductions (90.2 ± 4.03%) compared with controls, although blood parameters remained relatively unchanged probably because the level of challenge was low. Vaccination prevented the periparturient rise in egg shedding of ewes, as well as egg shedding in lambs (37.1%). In the second trial, sheep which were experimentally exposed to higher artificial challenge also showed an efficient response to the vaccine as confirmed by high antibody levels and reduced egg counts and worm burdens (87 ± 5.4% and 79%) respectively. Thus, we believe that the vaccine should be integrated with other management practices for meat hair sheep as it has the advantages of adequate efficacy, reducing anthelmintic utilization and avoiding milk and environmental contamination with chemical residues. Embrapa Caprinos e Ovinos, Fazenda Três Lagoas, Rodovia Sobral - Groaíras Km 04, Caixa Postal 145 Centro Universitário UNINTA Curso de Pós-Graduação em Zootecnia Universidade Estadual Vale do Acarau Curso de Pós-Graduação em Medicina Veterinária Universidade Federal de Santa Maria Universidade Estadual Júlio de Mesquita Filho UNESP-Botucatu Moredun Research Institute Pentlands Science Park Universidade Estadual Júlio de Mesquita Filho UNESP-Botucatu |
| Databáze: | OpenAIRE |
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