Low human exposure to styrene in relation to chromosome breaks, gaps and sister chromatid exchanges
| Autor: | Inger-Lise Hansteen, Birger FøRSUND, Øyvind Jelmert, Torgrim Torgrimsen |
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| Rok vydání: | 1984 |
| Předmět: |
Chromosome Aberrations
Cytogenetic investigation Smoking habit Physiology Sister chromatid exchange General Medicine Low level exposure Air Pollutants Occupational Biology Styrene Styrenes Toxicology chemistry.chemical_compound Chromosome Breaks chemistry Human exposure Genetics Sister chromatids Humans Crossing Over Genetic Sister Chromatid Exchange |
| Zdroj: | Hereditas. 100(1) |
| ISSN: | 0018-0661 |
| Popis: | Hansteen, I.-L., Jelmert, o., Torgrimsen, T. and Forsund, B. 1584. Low human exposure to styrene in relation to chromosome breaks, gaps and sister chromatid exchanges. —Hereditas 100: 87–91. Lund, Sweden. ISSN 0018–0661. Received May 30, 1983 Measurements of styrene concentration in air and determination of urine metabolites were performed each day for one week prior to taking blood samples for cytogenetic investigation, in order to compare these findings with the cytogenetic results. The results showed levels of styrene exposure well below the recommended level of 50 ppm for all the 18 workers tested. No increase in number of chromosome breaks and SCE's was found in the workers for this low level of styrene exposure compared to a control group. A significant increase in gaps was found in the workers, however, and the possibility of using gaps as an indication of low level exposure is discussed. When the material was grouped according to smoking habits, a significant increase in chromosome breaks was found in the smokers, but no increase in SCE was found, indicating that the SCE method must be applied with caution and on a large number of individuals when used for monitoring purposes. |
| Databáze: | OpenAIRE |
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