Supplementary Figure 6 from DLL4-Notch Signaling Mediates Tumor Resistance to Anti-VEGF Therapy In Vivo

Autor: Adrian L. Harris, Richard Poulsom, Craig P. Montgomery, Angela J. Russell, Partha S. Chowdhury, Herren Wu, Emma T. Bowden, Cameron Snell, Wen Shi, Esther Bridges, Helen Sheldon, Russell Leek, Helen Turley, Chern Ein Oon, Richard C.A. Sainson, Ji-Liang Li
Rok vydání: 2023
DOI: 10.1158/0008-5472.22388565
Popis: PDF file - 740K, Neither anti-EphrinB2 nor sEphB4 affected the growth of U87-EV tumors in vivo. Compared to the control, neutralizing anti-EphrinB2 antibody (B2) alone (blue arrowhead) did not affect the tumor growth. Also, combined anti-EphrinB2 antibody (blue arrowhead) with bevacizumab (purple arrowhead) did not increase the therapeutic efficacy of bevacizumab. Similar results were obtained for sEphB4. Mean � SE, N=5. **P
Databáze: OpenAIRE