Laboratory performance testing of venous cannulae during inlet obstruction

Autor: Yuri M. Ganushchak, Pieter Wortel, Antoine P. Simons, Theo van der Nagel, Frederik H. van der Veen, Jos G. Maessen, Dick S. de Jong
Rok vydání: 2008
Předmět:
Zdroj: Artificial organs. 32(7)
ISSN: 1525-1594
Popis: Venous cannulae undergo continuous improvements to achieve better and safer venous drainage. Several cannula tests have been reported, though cannula performance during inlet obstruction has never been a test criterion. In this study, five different cannulae for proximal venous drainage were tested in a mock circulation that enabled measurement of hydraulic conductance after inlet obstruction by vessel collapse. Values for hydraulic conductance ranged from 1.11 x 10(-2) L/min/mm Hg for a Thin-Flex Single Stage Venous Cannula with an open-end lighthouse tip to 1.55 x 10(-2) L/min/mm Hg for a DLP VAD Venous Cannula featuring a swirled tip profile, showing a difference that amounts to nearly 40% of the lowest conductance value. Excessive venous drainage results in potentially dangerous high-negative venous line pressures independent of cannula design. Cannulatip design featuring swirled and grooved tip structures increases drainage capacity and enhances cannula performance during inlet obstruction.
Databáze: OpenAIRE