Outcome of anticoagulation in isolated distal deep vein thrombosis compared to proximal deep venous thrombosis
Autor: | Damon E. Houghton, David O. Hodge, Ana I. Casanegra, Robert D. McBane, Ahmed K. Pasha, Launia J. White, David A. Froehling, Paul R. Daniels, Matthew A. Bartlett, Danielle T. Vlazny, Waldemar E. Wysokinski, Wiktoria Kuczmik |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Deep vein Recurrence Risk Factors medicine Humans cardiovascular diseases Embolization Thrombus Venous Thrombosis business.industry Mortality rate Warfarin Cancer Anticoagulants Hematology Venous Thromboembolism medicine.disease Thrombosis Surgery Venous thrombosis medicine.anatomical_structure Treatment Outcome business medicine.drug |
Zdroj: | Journal of thrombosis and haemostasis : JTHREFERENCES. 19(9) |
ISSN: | 1538-7836 |
Popis: | BACKGROUND Isolated, distal deep vein thrombosis (IDDVT) is thought to have low rates of propagation, embolization, and recurrence compared with proximal DVT (PDVT), but the data are limited. OBJECTIVES The objective of this study was to assess outcomes among patients with IDDVT compared with PDVT. PATIENTS/METHODS Consecutive patients with ultrasound-confirmed acute DVT (March 1, 2013-August 1, 2020) were identified by reviewing the Mayo Clinic Gonda Vascular Center and VTE Registry databases. Patients were divided into two groups depending on the DVT location (isolated, distal vs. proximal DVT). Outcomes including venous thromboembolism (VTE) recurrence, major bleeding, and death were compared by thrombus location and anticoagulant therapy, warfarin vs. direct oral anticoagulant (DOAC). RESULTS Isolated, distal deep vein thrombosis (n = 746) was more often associated with recent surgery, major trauma, or confinement (p |
Databáze: | OpenAIRE |
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