Outcome of anticoagulation in isolated distal deep vein thrombosis compared to proximal deep venous thrombosis

Autor: Damon E. Houghton, David O. Hodge, Ana I. Casanegra, Robert D. McBane, Ahmed K. Pasha, Launia J. White, David A. Froehling, Paul R. Daniels, Matthew A. Bartlett, Danielle T. Vlazny, Waldemar E. Wysokinski, Wiktoria Kuczmik
Rok vydání: 2021
Předmět:
Zdroj: Journal of thrombosis and haemostasis : JTHREFERENCES. 19(9)
ISSN: 1538-7836
Popis: BACKGROUND Isolated, distal deep vein thrombosis (IDDVT) is thought to have low rates of propagation, embolization, and recurrence compared with proximal DVT (PDVT), but the data are limited. OBJECTIVES The objective of this study was to assess outcomes among patients with IDDVT compared with PDVT. PATIENTS/METHODS Consecutive patients with ultrasound-confirmed acute DVT (March 1, 2013-August 1, 2020) were identified by reviewing the Mayo Clinic Gonda Vascular Center and VTE Registry databases. Patients were divided into two groups depending on the DVT location (isolated, distal vs. proximal DVT). Outcomes including venous thromboembolism (VTE) recurrence, major bleeding, and death were compared by thrombus location and anticoagulant therapy, warfarin vs. direct oral anticoagulant (DOAC). RESULTS Isolated, distal deep vein thrombosis (n = 746) was more often associated with recent surgery, major trauma, or confinement (p
Databáze: OpenAIRE