Choroideremia associated with choroidal neovascularization treated with intravitreal bevacizumab
| Autor: | Andreas K. Lauer, Neal V. Palejwala, Richard G. Weleber |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Visual acuity hereditary choroidal dystrophy business.industry intravitreal bevacizumab injection Case Report medicine.disease Choroideremia eye diseases Ophthalmology Left eye Choroidal neovascularization Choroidal neovascular membrane medicine anti-VEGF therapy choroidal neovascular membrane chorioretinal degeneration Subretinal fibrosis sense organs medicine.symptom Intravitreal bevacizumab business Hereditary choroidal dystrophy choroideremia |
| Zdroj: | Clinical Ophthalmology (Auckland, N.Z.) |
| ISSN: | 1177-5483 1177-5467 |
| Popis: | PURPOSE To report a rare case of central vision loss in a patient with choroideremia. PATIENTS AND METHODS A retrospective, interventional case report. RESULTS A 13-year-old male with history of choroideremia presented with subacute loss of central acuity in his left eye. Examination and diagnostic testing revealed subretinal fibrosis secondary to a choroidal neovascular membrane (CNVM). A trial of anti-vascular endothelial growth factor (VEGF) therapy with the injection of intravitreal bevacizumab was attempted. Mild improvements in acuity and anatomy were noted. CONCLUSION Choroideremia is a rare hereditary choroidal dystrophy that predominantly affects males in the first and second decades of life. Visual acuity is usually spared until later in life. CNVM is a rare manifestation of choroideremia with only a handful of case reports presented in the literature. This case is unique in that it is the first reported case that received treatment with intravitreal anti-VEGF therapy. |
| Databáze: | OpenAIRE |
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