Neurological disability in HTLV-1 infected individuals according to the initial clinical presentation: cohort study

Autor: Tânia Luna, Michael Sundberg, Katia Viana, Matheus Tannus, Davi Costa, Valéria Gusmão, Edgar M. Carvalho, Taís Dellavechia, André Muniz dos Santos, Lorena Dantas, Anselmo Souza, Glória Orge, Néviton Castro, Silvany Braga
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Retrovirology, Vol 8, Iss Suppl 1, p A62 (2011)
Retrovirology
ISSN: 1742-4690
Popis: Background It’s estimated that 10 to 20 million people are infected with the HTLV-1 virus worldwide. Two principal diseases are associated with this virus: the Adult T-cell Lymphoma/Leukemia (ATLL), and the HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/ TSP). The last one is a debilitating neurological disease characterized by a chronic progressive paraparesis, with autonomic and mild sensorial complains. There are also incomplete forms of HAM/TSP, sometimes called subclinical or oligosymptomatic. Those mild and moderate neurological presentations are found in almost one fourth of the HTLV-1 patients and they include neurogenic bladder syndromes, erectile dysfunction, isolated pyramidal signs and peripheral neuropathy.
Databáze: OpenAIRE