Role of age and birth month in infants hospitalized with RSV‐confirmed disease in the Valencia Region, Spain

Autor: Ainara Mira-Iglesias, Clarisse Demont, Javier García-Rubio, Mario Carballido-Fernández, Beatriz Mengual-Chuliá, other Respiratory Viruses, F. Xavier López-Labrador, Germán Schwarz-Chavarri, Juan Mollar-Maseres, Miguel Tortajada-Girbés, Javier Díez-Domingo, Joan Puig-Barberà
Přispěvatelé: UCH. Departamento de Medicina y Cirugía, Producción Científica UCH 2022
Rok vydání: 2021
Předmět:
Pulmonary and Respiratory Medicine
Virus sincitial respiratorio - Diagnóstico - España - Valencia (Comunidad Valenciana)
Pediatrics
medicine.medical_specialty
Epidemiology
respiratory syncytial virus
Niños - Cuidados hospitalarios - España - Valencia (Comunidad Autónoma)
viruses
Population
Children - Virus diseases - Spain - Valencia (Autonomous Community)
Respiratory Syncytial Virus Infections
Disease
Central laboratory
medicine
Humans
Niños - Enfermedades víricas - España - Comunidad Valenciana
hospitalizations
Child
education
education.field_of_study
infants
business.industry
Incidence
Birth Month
Public Health
Environmental and Occupational Health
Infant
virus diseases
Emergency department
respiratory system
Respiratory syncytial virus - Diagnosis - Spain - Valencia (Autonomous Community)
medicine.disease
Hospitalization
Infectious Diseases
Spain
Bronchiolitis
Child
Preschool
surveillance
SARS-CoV-2 (Virus) - Diagnosis - 2019-2020 - Spain - Valencia (Autonomous Community)
Seasons
Children - Hospital care - Spain - Valencia (Autonomous Community)
business
Zdroj: CEU Repositorio Institucional
Fundación Universitaria San Pablo CEU (FUSPCEU)
INFLUENZA AND OTHER RESPIRATORY VIRUSES
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
ISSN: 1750-2659
1750-2640
DOI: 10.1111/irv.12937
Popis: Este artículo se encuentra disponible en la siguiente URL: https://onlinelibrary.wiley.com/doi/epdf/10.1111/irv.12937 En este artículo de investigación también participan: Miguel Tortajada-Girbés, Juan Mollar-Maseres, Germán Schwarz-Chavarri, Joan Puig-Barberà, Javier Díez-Domingo y la Valencia Hospital Network for the Study of Influenza and other Respiratory Viruses. Background: RSV is the leading cause of hospital admissions in infants and the principal cause of bronchiolitis in young children. There is a lack of granular data on RSVassociated hospitalization per season using laboratory confirmed results. Our current study addresses this issue and intends to fill this gap. Methods: The study was conducted from 2014 through 2018, in 4 to 10 hospitals in the Valencia Region, Spain. Infants included in this study were admitted in hospital through the Emergency Department with a respiratory complaint and tested by RTPCR for RSV in a central laboratory. Results: Incidence rates of RSV-associated hospitalization varied by season and hospital. Overall, the highest incidence rates were observed in 2017/2018. RSVassociated hospitalization was highest in infants below 3 months of age and in those born before or at the beginning of the RSV season. Almost 54% of total infants hospitalized with laboratory confirmed RSV were found to be born outside the season, from April to October. The RSV positivity rate by ICD-10 discharged codes varied by season and age with results from 48% to 57% among LRI (J09-J22). Conclusion: The study was instrumental in bringing forth the time unpredictability of RSV epidemics, the critical impact of age, and the comparable distribution of RSVassociated hospitalization in infants born on either side of the RSV season. These data could help in better characterization of the population that drives the healthcare burden and is crucial for the development of future immunization strategies, especially with upcoming vaccines in against RSV.
Databáze: OpenAIRE
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