Experiences and challenges in the management of pregnancy-associated breast cancer at the Korle Bu Teaching Hospital: a review of four cases
| Autor: | Rita Appiah-Danquah, Joel Yarney, Theodore Wordui, Aba Anoa Scott, Florence Dedey, Nelson K. R. Damale, Josephine Nsaful, Joe-Nat Clegg-Lamptey, Samuel A. Oppong, Benjamin Fenu, Verna Vanderpuye |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Cancer Research
medicine.medical_specialty Pregnancy business.industry pregnancy-associated breast cancer Gestational age Cancer gestational breast cancer Case Report Disease Malignancy medicine.disease Systemic therapy 03 medical and health sciences 0302 clinical medicine Breast cancer Oncology 030220 oncology & carcinogenesis medicine 030212 general & internal medicine Stage (cooking) Intensive care medicine business multidisciplinary team |
| Zdroj: | ecancermedicalscience |
| ISSN: | 1754-6605 |
| Popis: | Breast cancer is the commonest female cancer worldwide and the most common malignancy during pregnancy. The current management of breast cancer is based on patient and tumour characteristics, preferences and disease stage. In pregnancy-associated breast cancer, the gestational age influences treatment options. Sequencing of therapies is guided by safe imaging options, timing of delivery and prognosis. Systemic therapy options in the neoadjuvant, adjuvant and palliative settings are limited due to safety concerns of the unborn foetus. In resource-constrained regions, the application of safe options may be challenging. This paper reports four of such cases managed in Ghana using a multidisciplinary approach and local resource-appropriate evidence-based practices. Maternal and foetal outcomes were acceptable with none resulting in termination of pregnancy. |
| Databáze: | OpenAIRE |
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