Chemical approaches to deciphering the glycosaminoglycan code

Autor:	Linda C. Hsieh-Wilson, Cristal I. Gama
Rok vydání:	2005
Předmět:	Cell growth Extramural Heparin Sulfates Chondroitin Sulfates Biology Biochemistry Models Biological Analytical Chemistry Glycosaminoglycan Sulfation Biopolymers Polysaccharides Chemical diversity Animals Humans Growth Substances Glycosaminoglycans
Zdroj:	Current opinion in chemical biology. 9(6)
ISSN:	1367-5931
Popis:	Glycosaminoglycans are sulfated biopolymers with rich chemical diversity and complex functions in vivo, contributing to processes ranging from cell growth and neuronal development to viral invasion and neurodegenerative disease. Recent studies suggest that glycosaminoglycans may encode information in the form of a ‘sulfation code,’ whereby discrete modifications to the polysaccharide backbone may direct the location or activities of proteins.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae227835f12304153f3d923eff7eae26 https://pubmed.ncbi.nlm.nih.gov/16242378 Zobrazit plný text záznamu Full Text from ScienceDirect