Negative T waves shortly after ST-elevation acute myocardial infarction are a powerful marker for improved survival rate
| Autor: | Sergio L. Pinski, Kathy B. Gates, Eric J. Topol, Alejandro Barbagelata, Galen S. Wagner, Peter M. Meyer, Biljana Pavlovic-Surjancev, Andrea S. Lum, Donald A. Underwood, Elena B. Sgarbossa, Shaun G. Goodman, Robert M. Califf |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Streptokinase Myocardial Infarction Infarction Coronary Angiography Sensitivity and Specificity Electrocardiography Fibrinolytic Agents Internal medicine T wave medicine Humans Myocardial infarction Prospective Studies Survival rate Aged business.industry ST elevation Thrombolysis Middle Aged medicine.disease Prognosis Survival Rate Cardiology Female Myocardial infarction diagnosis Cardiology and Cardiovascular Medicine business Biomarkers medicine.drug |
| Zdroj: | American heart journal. 140(3) |
| ISSN: | 0002-8703 |
| Popis: | Background Recent studies have reported that negative T waves in the setting of acute coronary events are associated with Thrombolysis In Myocardial Infarction flow grade 3 in the infarct-related artery and with improved parameters of ventricular function rather than with ischemia. Methods Patients enrolled in the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO-I) angiographic substudy (ie, patients with acute infarction randomly assigned to one of 4 thrombolytic regimens who then underwent coronary angiography) were included in this study if they survived at least 24 hours and had no confounding electrocardiographic factors (n = 1505). Results More patients had negative T waves develop (NT group, n = 938 [62%]) than not (PT group, n = 567 [38%]). Peak creatine kinase MB, time to thrombolysis, and randomization to accelerated alteplase were no different between the groups. Thirty days after admission, 12 patients in the NT group had died versus 25 patients in the PT group (1.3% vs. 4.4%; P |
| Databáze: | OpenAIRE |
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