Green tea polyphenols and their potential role in health and disease
Autor: | M. Menon, A. M. Safer, M. Afzal |
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Rok vydání: | 2015 |
Předmět: |
Antioxidant
medicine.medical_treatment Immunology Inflammation Disease Resveratrol Epigallocatechin gallate Pharmacology medicine.disease_cause Antioxidants Catechin chemistry.chemical_compound medicine Animals Humans Pharmacology (medical) Tea Polyphenols food and beverages Oxidative Stress Mechanism of action chemistry Biochemistry Polyphenol medicine.symptom Oxidation-Reduction Oxidative stress |
Zdroj: | Inflammopharmacology. 23:151-161 |
ISSN: | 1568-5608 0925-4692 |
DOI: | 10.1007/s10787-015-0236-1 |
Popis: | There is a growing body of evidence that plant polyphenols such as resveratrol, anthocyanins, catechins, and terpenes like taxol are effectively used in the treatment of chronic conditions including cancer, Alzheimer, Parkinsonism, diabetes, aging, etc. The link between oxidative stress and inflammation is well accepted. Thus, the mechanism of action of these natural products is partly believed to be through their significant antioxidant properties. The main constituent of green tea, with clinical significance, is epigallocatechin gallate (EGCG). It has been associated with antitumor, anti-Alzheimer, and anti-aging properties, improve redox status at the tissue level possibly preventing system level structural damage. This review focuses on EGCG and its potential therapeutic role in health and disease. |
Databáze: | OpenAIRE |
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