Evaluation of a cognitive behaviourally oriented service for relapse prevention in schizophrenia

Autor:	Stefan Klingberg, G. Buchkremer, K. Jakob-Deters, Andreas Wittorf, Georg Wiedemann, A. Fischer
Rok vydání:	2010
Předmět:	Adult Hospitals Psychiatric Male medicine.medical_specialty Psychological intervention Relapse prevention Young Adult Germany Health care Secondary Prevention medicine Humans Psychiatry Survival analysis Psychiatric Status Rating Scales Cognitive Behavioral Therapy Dose-Response Relationship Drug Positive and Negative Syndrome Scale business.industry Cognition Middle Aged medicine.disease Combined Modality Therapy Log-rank test Psychiatry and Mental health Treatment Outcome Psychotic Disorders Schizophrenia Physical therapy Female Schizophrenic Psychology Psychology business Antipsychotic Agents
Zdroj:	Acta Psychiatrica Scandinavica. 121:340-350
ISSN:	1600-0447 0001-690X
Popis:	Klingberg S, Wittorf A, Fischer A, Jakob-Deters K, Buchkremer G, Wiedemann G. Evaluation of a cognitive behaviourally oriented service for relapse prevention in schizophrenia. Objective: There is little work demonstrating the effectiveness of cognitive behaviourally oriented interventions in routine service settings. This pragmatic trial is designed to test the impact of a group treatment service on relapse rates under the conditions of routine health care. Method: A total of 169 schizophrenia patients were randomly allocated either to a comprehensive cognitive behaviourally oriented service (CBOS) or to treatment as usual (TAU). The primary outcome is the time until the first relapse after discharge from hospital. Relapse was defined as an increase in positive or negative symptoms as assessed with the Positive and Negative Syndrome Scale. Survival analysis has been conducted up to the 6-month assessment. Results: The mean time to relapse after discharge from hospital in the CBOS group was significantly longer than in the TAU group (log rank test, P = 0.033). This was due to less exacerbations regarding negative symptoms in the CBOS condition (log rank test, P = 0.014). The number of social contacts was improved in the CBOS group only. Conclusion: The CBOS intervention appears to be beneficial in reducing early negative symptom exacerbations.
Databáze:	OpenAIRE
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