Coccidioidomycosis in a Patient with Lymphoma: Spherulation in Human Pleural Fluid Medium
| Autor: | Arif S. El-Ani, John E. Fitzpatrick, John W. Pickren |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Pathology
medicine.medical_specialty Necrosis Coccidioides immitis Follicular lymphoma Caseous necrosis Biology Lesion Agar plate medicine Humans Lymphoma Follicular Coccidioidomycosis Coccidioides Lung Diseases Fungal General Medicine Middle Aged Spores Fungal medicine.disease biology.organism_classification Culture Media Lymphoma Pleural Effusion Abdominal Neoplasms Granuloma Female medicine.symptom |
| Zdroj: | American Journal of Clinical Pathology. 70:423-428 |
| ISSN: | 1943-7722 0002-9173 |
| DOI: | 10.1093/ajcp/70.3.423 |
| Popis: | In a Caucasian woman who had had a giant follicular lymphoma for 21 months a small lesion developed in the upper lobe of the left lung. Excision, histologic study, and culture of the lesion were performed. Of the many stained sections, only one revealed endospore-containing spherules within the caseous necrosis of a granuloma, and only four spherules were identified. On agar medium the same tissue yielded a fast-growing fungus that produced arthrospores alternating with empty cells, typical of Coccidioides immitis . The arthrospore suspension was inoculated intraperitoneally into a mouse and into a medium of human pleural fluid at 40 C. Spherules containing endospores developed in the in-ternal organs of the mouse and in the pleural fluid medium. The phylogeny of C . immitis is briefly discussed. |
| Databáze: | OpenAIRE |
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