An Efficient Synthesis of Phenanthroindolizidine Core via Hetero Diels-Alder Reaction of In Situ Generated α-Allenylchalcogenoketenes With Cyclic Imines

Autor:	Mariko Suzuki, Yuji Takikawa, Toshinobu Korenaga, Shigenobu Aoyagi, Kazuaki Shimada, Kohei Yahaba
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Pharmacology In situ indolizidine 010405 organic chemistry Chemistry α-allenylselenoketene alkynyl propargyl selenide hetero Diels-Alder reaction alkynyl propargyl sufide Core (manufacturing) Indolizidine Plant Science General Medicine 01 natural sciences 0104 chemical sciences phenanthroindolizidine 010404 medicinal & biomolecular chemistry chemistry.chemical_compound Complementary and alternative medicine Drug Discovery Polymer chemistry α-allenylthioketene Diels–Alder reaction
Zdroj:	Natural Product Communications. 14(6):1-13
ISSN:	1934-578X
Popis:	Synthesis of phenanthroindolizidine core was efficiently achieved through a pathway involving hetero Diels-Alder reaction of α-allenylchalcogenoketenes, generated in situ by thermal [3,3] sigmatropic rearrangement of alkynyl propargyl sulfides or selenides, with cyclic imines and the subsequent iodine-assisted photochemical cyclization.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acdb10a5204cfed6f0a77ce8539b30e2 https://iwate-u.repo.nii.ac.jp/records/14922 Zobrazit plný text záznamu