Toxic Effect of Aflatoxins in Dogs Fed Contaminated Commercial Dry Feed: A Review
| Autor: | Raul Ortiz-Martinez, Lizbeth Martínez-Martínez, Alma Lilián Guerrero-Barrera, Teódulo Quezada-Tristán, Erika Janet Rangel-Muñoz, Arturo Valdivia-Flores |
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| Rok vydání: | 2020 |
| Předmět: |
Aflatoxin
040301 veterinary sciences Health Toxicology and Mutagenesis Secondary infection lcsh:Medicine Secondary Metabolism Aspergillus flavus Food Contamination Review Biology Toxicology Hepatic Diseases blood coagulation 0403 veterinary science Foodborne Diseases 0404 agricultural biotechnology Dogs Aflatoxins Animals Dog Diseases aflatoxicosis lcsh:R Fungi Mycotoxicosis biomarkers 04 agricultural and veterinary sciences Contamination biology.organism_classification 040401 food science Animal Feed hepatic diseases |
| Zdroj: | Toxins Toxins, Vol 13, Iss 65, p 65 (2021) |
| ISSN: | 2072-6651 |
| Popis: | Since its first patent (1897), commercial dry feed (CDF) for dogs has diversified its formulation to meet the nutritional needs of different breeds, age, or special conditions and establish a foundation for integration of these pets into urban lifestyles. The risk of aflatoxicosis in dogs has increased because the ingredients used to formulate CDF have also proliferated, making it difficult to ensure the quality required of each to achieve the safety of the entire CDF. This review contains a description of the fungi and aflatoxins detected in CDF and the ingredients commonly used for their formulation. The mechanisms of action and pathogenic effects of aflatoxins are outlined; as well as the clinical findings, and macroscopic and microscopic lesions found in aflatoxicosis in dogs. In addition, alternatives for diagnosis, treatment, and control of aflatoxins (AF) in CDF are analyzed, such as biomarkers of effect, improvement of blood coagulation, rate of elimination of AF, control of secondary infection, protection of gastric mucosa, reduction of oxidative stress, use of chemo-protectors, sequestrants, grain-free CDF, biocontrol, and maximum permitted limits, are also included. |
| Databáze: | OpenAIRE |
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