Problem Based Review: The patient who has taken an overdose of long-acting insulin analogue
| Autor: | K F Hunt, Omar G Mustafa, Benjamin Whitelaw, A E Eldred |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Blood glucose monitoring
Type 1 diabetes medicine.medical_specialty medicine.diagnostic_test Insulin glargine business.industry Insulin medicine.medical_treatment General Medicine Critical Care and Intensive Care Medicine medicine.disease Drug overdose Diabetes mellitus Anesthesia Blood Glucose Self-Monitoring Emergency Medicine Internal Medicine medicine Intensive care medicine business medicine.drug Insulin detemir |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1747-4884 |
| DOI: | 10.52964/amja.0312 |
| Popis: | Insulin overdose can cause harm due to hypoglycaemia, effects on electrolytes and acute hepatic injury. The established long-acting insulin analogue preparations (detemir and glargine) can present specific management problems because, in overdose, their effects are extremely prolonged, often lasting 48-96 hours. The primary treatment is continuous intravenous 10% or 20% glucose infusion with frequent capillary blood glucose monitoring. Surgical excision of the insulin injection site has been used successfully, even days after the overdose occurred. Once the effects of overdose have receded, diabetes treatment must be restarted with care, especially in patients with type 1 diabetes. Monitoring serum insulin concentration has been successfully used to predict when the effects of the overdose will cease. |
| Databáze: | OpenAIRE |
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