Ampicillin resistance in Neisseria denitrificans: studies on ampicillin-sensitive enzymes
| Autor: | K. G. Johnson, I. J. McDonald, C. R. MacKenzie |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Penicillin Resistance
Immunology Neisseria denitrificans Carboxypeptidases Peptidoglycan Muramoylpentapeptide Carboxypeptidase Applied Microbiology and Biotechnology Microbiology chemistry.chemical_compound Glutamates Amp resistance Ampicillin Genetics medicine Molecular Biology chemistry.chemical_classification biology Strain (chemistry) Glutamate receptor General Medicine Carboxypeptidase Enzyme chemistry Biochemistry biology.protein Neisseria medicine.drug |
| Zdroj: | Canadian Journal of Microbiology. 27:553-557 |
| ISSN: | 1480-3275 0008-4166 |
| DOI: | 10.1139/m81-083 |
| Popis: | The β-lactam sensitivities of enzymes involved in peptidoglycan synthesis were examined in two strains of Neisseria 'enitrificans having widely disparate degrees of ampicillin sensitivity. One strain of N. denitrificans was 400 times more resistant) ampicillin than the other; the former is known to have altered pencillin-binding proteins. No differences in the levels of ensitivities of total peptidoglycan synthesis as measured by the incorporation of glutamate into peptidoglycan, or of D-alanine arboxypeptidase, were observed between the two strains. However, the rate of glutamate incorporation into peptidoglycan by garithmic growth phase cells was somewhat less for the ampicillin-resistant cells than for the parent cells. |
| Databáze: | OpenAIRE |
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