A Survey of the Use of Iterative Reconstruction Algorithms in Electron Microscopy

Autor: J. Cuenca, Roberto Marabini, Pablo Conesa, Roberto Melero, José Luis Vilas, L. del Cano, Josué Gómez-Blanco, Javier Vargas, José María Carazo, J.M. de la Rosa-Trevín, Mohsen Kazemi, Joaquín Otón, Carlos Oscar S. Sorzano
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: BioMed Research International, Vol 2017 (2017)
BioMed Research International
ISSN: 2314-6141
2314-6133
Popis: One of the key steps in Electron Microscopy is the tomographic reconstruction of a three-dimensional (3D) map of the specimen being studied from a set of two-dimensional (2D) projections acquired at the microscope. This tomographic reconstruction may be performed with different reconstruction algorithms that can be grouped into several large families: direct Fourier inversion methods, back-projection methods, Radon methods, or iterative algorithms. In this review, we focus on the latter family of algorithms, explaining the mathematical rationale behind the different algorithms in this family as they have been introduced in the field of Electron Microscopy. We cover their use in Single Particle Analysis (SPA) as well as in Electron Tomography (ET).
Databáze: OpenAIRE