Performance of the ASAS Health Index for the Evaluation of Spondyloarthritis in Daily Practice
| Autor: | Sara Alonso-Castro, Luis Arboleya, Estefanía Pardo, Lilyan Charca, Rubén Queiro, Sabela Fernández, Marina Pino, Mercedes Alperi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Multivariate statistics Immunology Severity of Illness Index Likelihood ratios in diagnostic testing Spearman's rank correlation coefficient 03 medical and health sciences Health index 0302 clinical medicine Rheumatology Interquartile range Surveys and Questionnaires Daily practice Spondylarthritis medicine Humans Immunology and Allergy Spondylitis Ankylosing 030212 general & internal medicine 030203 arthritis & rheumatology business.industry Clinical performance Reproducibility of Results Cross-Sectional Studies Convergent validity Physical therapy business |
| Zdroj: | The Journal of Rheumatology. 47:1483-1489 |
| ISSN: | 1499-2752 0315-162X |
| DOI: | 10.3899/jrheum.200025 |
| Popis: | ObjectiveThe Assessment of SpondyloArthritis international Society Health Index (ASAS HI) is a tool designed to assess disease impact in spondyloarthritis (SpA), but its clinical performance is barely known. We aimed to test the clinimetric properties of ASAS HI in a real clinical setting.MethodsThis cross-sectional study included 111 consecutive patients with SpA. The measurement properties of ASAS HI were tested against conventional assessment measures. Convergent validity was assessed by Spearman rho correlations, while discriminative validity was analyzed through receiver-operating characteristic (ROC) curves. A multivariate regression analysis was designed to identify ASAS HI items associated with active disease.ResultsThe average ASAS HI was 5.4 ± 3.8 (interquartile range 3–8). ASAS HI showed high convergent validity against other SpA measures (rho ≥ 0.70, p < 0.0005). The optimal criteria for detecting high/very high disease activity Ankylosing Spondylitis Disease Activity Score (ASDAS) categories was an ASAS HI score > 6, area under the ROC curve 0.86 (95% CI 0.78–0.92), positive likelihood ratio 7.3 (95% CI 3.1–17.1), p < 0.0001. The ASAS HI items significantly associated with Bath Ankylosing Spondylitis Disease Activity Index active disease were “I often get frustrated” (OR 9.2, 95% CI 1.2–69.4, p = 0.032), and “I sleep badly at night” (OR 7.7, 95% CI 1.4–41.6, p = 0.018). As for ASDAS, it was “pain sometimes disrupts my normal activities” (OR 8.7, 95% CI 1.7–45.2, p = 0.010).ConclusionThe ASAS HI is a useful and simple instrument for its application in daily practice. Given its good clinimetric properties, it could be used as an additional instrument to evaluate SpA. |
| Databáze: | OpenAIRE |
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