The surface morphology of normal and malignant rat liver epithelial cells in culture

Autor: T. D. Allen, P. T. Iype, Martin J. Murphy
Rok vydání: 1976
Předmět:
Zdroj: In Vitro. 12:837-844
ISSN: 1475-2689
0073-5655
DOI: 10.1007/bf02796369
Popis: A direct comparison has been made between normal parenchymal cells cultured from rat liver and malignant cells from both a rat liver tumor and a spontaneously transformed line derived from the parent rat culture. In all nondividing cells there was a 3- to 5-fold increase in the population of surface microvilli on the malignant cells compared to the normal cells. Notable variations in overall morphology were also observed when cells were incubated in arginine-deficient medium.
Databáze: OpenAIRE