Non-contact measurement of thermal diffusivity in tissue
| Autor: | Thomas E. Milner, Sergey A. Telenkov, Dennis M. Goodman, Ashley J. Welch, Jong In Youn |
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| Rok vydání: | 2001 |
| Předmět: |
Pulsed laser
Point spread function Adult Materials science Infrared Infrared Rays Swine Physics::Medical Physics Biophysics In Vitro Techniques Thermal diffusivity Biophysical Phenomena Body Temperature Diffusion Optics Thermal Animals Humans Radiology Nuclear Medicine and imaging Radiological and Ultrasound Technology business.industry Phantoms Imaging Nonlinear system Heat equation Laser Therapy Epidermis business Excitation |
| Zdroj: | Physics in medicine and biology. 46(2) |
| ISSN: | 0031-9155 |
| Popis: | We demonstrate the application of an infrared (IR) imaging technique for non-contact determination of thermal diffusivity in biological materials. The proposed method utilizes pulsed laser excitation to produce an initial three-dimensional temperature distribution in tissue, and records IR images of subsequent heat diffusion. The theoretical model assumes that the time-dependent temperature increase following pulsed laser exposure is due to independent heat diffusion in longitudinal and lateral directions. A nonlinear least-squares algorithm is used to compute the lateral thermal point spread function from a pair of recorded IR images and to determine the thermal diffusivity of a test specimen. The recorded time-sequence of IR images is used to compute thermal diffusivity as a function of increasing time interval between two IR emission images. Experimental application of the method was demonstrated using tissue phantoms, ex vivo samples of hydrated cartilage and in vivo epidermis. |
| Databáze: | OpenAIRE |
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