Evaluation of Treatment Patterns and Direct Costs Associated with the Management of Neuropathic Pain
| Autor: | Andrés Gaviria-Mendoza, Jorge Enrique Machado-Alba, Natalia Castano, Manuel Enrique Machado-Duque |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Medicine (General) medicine.medical_specialty Article Subject Population Pregabalin Colombia Time-to-Treatment Cohort Studies Indirect costs R5-920 Internal medicine medicine Humans Pain Management Amitriptyline Longitudinal Studies Practice Patterns Physicians' education Analgesics education.field_of_study business.industry Health Care Costs Carbamazepine Middle Aged Anesthesiology and Pain Medicine Neurology Neuropathic pain Cohort Neuralgia Female Tramadol business medicine.drug Research Article |
| Zdroj: | Pain Research & Management Pain Research and Management, Vol 2020 (2020) |
| ISSN: | 1918-1523 1203-6765 |
| Popis: | Background. Neuropathic pain has a prevalence of 2–17% in the general population. Diagnosis and treatment of neuropathic pain are not fully described in different populations. The aim was to determine the treatment patterns and direct costs of care associated with the management of neuropathic pain from the onset of the first symptom to up to two years after diagnosis. Methods. From a drug-claim database, a cohort of randomly selected outpatients diagnosed with neuropathic pain was obtained from an insurer in Colombia and followed up for two years after diagnosis. The clinical records were reviewed individually to identify the study variables, including the time needed to make the diagnosis, the medical and paraclinical resources used, the pharmacological therapy for pain management, and the direct costs associated with care. Results. We identified 624 patients in 49 cities, with a mean age of 50.3 ± 14.1 years, of which 324 were men (51.9%). An average of 90 days passed from the initial consultation until the diagnosis of neuropathic pain, the most frequent being lumbosacral radiculopathy (57.9%). 34.5% of the cohort had at least one diagnostic imaging procedure, and 16% had an electromyography. On average, they were treated by a general practitioner twice. 91.7% received initial treatment with tramadol, carbamazepine, amitriptyline, imipramine, or pregabalin, and 60.4% received combined therapy. The mean cost of care for two years for each patient was US$246.3. Conclusions. Patients with neuropathic pain in Colombia are being diagnosed late, are using therapeutic agents not recommended as first-line treatment by clinical practice guidelines, and are being treated for short periods of time. |
| Databáze: | OpenAIRE |
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